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Latest Research

ABCB1AzoleIDO1KynurenineMultidrug resistance
Discovery of a novel miconazole analogue as a dual apo-IDO1 inhibitor and ABCB1 modulator for cancer immunotherapy and chemosensitizing
Author：Pin-Chen Chen, Yung-Chieh Chang, Yun-Yun Ho, Kai-Yu Tseng, Kai-Hsuan Lin, Suat Sari, Zeynep Özdemir, Jóhannes Reyniss...
BIRC5 Promoter-Driven Nanodrugs Suppress BIRC5-Positive Cancers Independent of ABCB1 Status and IDO1 Expression 論文圖片
BIRC5 Promoter-Driven Nanodrugs Suppress BIRC5-Positive Cancers Independent of ABCB1 Status and IDO1 Expression
Author：Yung-Chieh Chang, Wei-Lun Huang, Wu-Chou Su, Euphemia Leung, Chun Hei Antonio Cheung
Publication Date：2026/04
Source：International Jo...
BDNF Val66Met protects oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer論文封面圖
BDNF Val66Met protects oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer
Author：Li-Hsien Chen; Peng-Chan Lin; Yu-Min Yeh; Chung-I Li; Lian-Yun Chang; Jang-Yang Chang; Meng-Ru Shen*
Publication Date：2026/02
Source：...
Reduction of Dietary Fat Rescues High-Fat Diet-Induced Depressive Phenotypes and the Associated Hippocampal Astrocytic Deficits in Mice論文封面圖片
Reduction of Dietary Fat Rescues High-Fat Diet-Induced Depressive Phenotypes and the Associated Hippocampal Astrocytic Deficits in Mice
Author：Kai-Pi Cheng, Hsin-Hao Chao , Chin-Ju Hsu, Sheng-Feng Tsai , Yen-Ju Chiu , Yu-Min Kuo, Yun-Wen Chen
Publication Date：2025/07
Source：M...
Deubiquitinase USP24 activated by IL-6/STAT3 enhances PD-1 protein stability and suppresses T cell antitumor response論文封面圖
Deubiquitinase USP24 activated by IL-6/STAT3 enhances PD-1 protein stability and suppresses T cell antitumor response
Author：Hung-Chia Hsieh, Ming-Jer Young,Kuan-Yu Chen, Wu-Chou Su, Chien-Chung Lin, Yi-Ting Yen,Jan-Jong Hung and Yi-Ching Wan...
Decreased plasma gelsolin fosters a fibrotic tumor microenvironment and promotes chemoradiotherapy resistance in esophageal squamous cell carcinoma論文封面圖
Decreased plasma gelsolin fosters a fibrotic tumor microenvironment and promotes chemoradiotherapy resistance in esophageal squamous cell carcinoma
Author：Chih-Hsiung Hsieh, Pei-Shiuan Ho, Wen-Lun Wang, Fu-Hsuan Shih, Chen-Tai Hong, Pei-Wen Wang, Dar-Bin Shieh, Wei-Lun Ch...

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