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Anxiety is a normal response when an animal is expecting a threat to his life. It is adaptive and signals danger that contributes to the mastery of a difficult situation. However, excessive anxiety is pathological either because it is too intense or because it is inappropriately provoked by events that present no real danger. Anxiety disorders are the most common psychiatric disorders, found in 10-30% of general population. Currently, the research interest in my laboratory is directed toward analyzing the roles of AMPA receptors, protein kinases and transcriptional factors in the acquisition and extinction of fear memory.

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Epilepsy continues to be a common and important health, psychosocial and socioeconomic problems. Despite the intensive researches on this field, the pathogenesis of epilepsy remains unresolved. Nuclear factor-kB (NF-kB) is a DNA-binding factor that is involved in neuroprotection or neurodegeneration depending on the particular system under investigation. We are interested in investigating the involvement of NF-kB in epileptiform activity.

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Neuropharmacology

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Electrophysiology

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Research NCKU！（Open Link）