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Latest Research

Decreased plasma gelsolin fosters a fibrotic tumor microenvironment and promotes chemoradiotherapy resistance in esophageal squamous cell carcinoma

Author:Chih-Hsiung Hsieh, Pei-Shiuan Ho, Wen-Lun Wang, Fu-Hsuan Shih, Chen-Tai Hong, Pei-Wen Wang, Dar-Bin Shieh, Wei-Lun Chang & Yi-Ching Wang
Date:2024/09
Source:Journal of Biomedical Science (2024) 31:90

Dysregulation of SOX17/NRF2 axis confers chemoradiotherapy resistance and emerges as a novel therapeutic target in esophageal squamous cell carcinoma

Author:Chih-Hsiung Hsieh, Wen-Hui Kuan, Wei-Lun Chang, I-Ying Kuo, Hsun Liu, Dar-Bin Shieh, Hsuan Liu, Bertrand Tan & Yi-Ching Wang
Date:2022/10
Source:Journal of Biomedical Science volume 29, Article number: 90 (2022)

The double-edged sword effect of HDAC6 in Aβ toxicities.

Author:Cheng KC, Hwang YL, Chiang HC.
Date:2022/01
Source:FASEB J. 2022 Jan;36(1):e22072. doi: 10.1096/fj.202101061R.

Early Aβ42 Exposure Causes Learning Impairment in Later Life.

Author:Cheng KC, Cheung CHA, Chiang HC.
Date:2022/06
Source:Aging Dis. 2022 Jun 1;13(3):868-883

Disrupted cellular calcium homeostasis is responsible for Aβ-induced learning and memory damage and lifespan shortening in a model of Aβ transgenic fly.

Author:Cheng KC, Huang CY, Hsieh TC, Chiang HC.
Date:2022/08
Source:IUBMB Life. 2022 Aug;74(8):754-762.

Development of a cancer cells self‑activating and miR‑125a‑5p expressing poly‑pharmacological nanodrug for cancer treatment

Author:Chang YC, Shieh MC, Chang YH, Huang WL, Su WC, Cheng FY, Cheung CHA.
Date:2022/08
Source:Int J Mol Med. 2022 Aug;50(2):102.

A dorsal CA2 to ventral CA1 circuit contributes to oxytocinergic modulation of long-term social recognition memory

Author:Tsai TC, Fang YS, Hung YC, Hung LC, Hsu KS.
Date:2022/07
Source:J Biomed Sci. 2022 Jul 10;29(1):50

Distinct Contribution of Granular and Agranular Subdivisions of the Retrosplenial Cortex to Remote Contextual Fear Memory Retrieval

Author:Tsai TC, Yu TH, Hung YC, Fong LI, Hsu KS.
Date:2022/02
Source:J Neurosci . 2022 Feb 2;42(5):877-893

TNFα-mediated necroptosis in brain endothelial cells as a potential mechanism of increased seizure susceptibility in mice following systemic inflammation

Author:Huang WY, Lai YL, Liu KH, Lin S, Chen HY, Liang CH, Wu HM, Hsu KS.
Date:2022/02
Source:J Neuroinflammation. 2022; 19: 29.

Discovery of Potential Neuroprotective Agents against Paclitaxel-Induced Peripheral Neuropathy.

Author:Chen YF, Wu CH, Chen LH, Lee HW, Lee JC, Yeh TK, Chang JY, Chou MC, Wu HL, Lai YP, Song JS, Yeh KC, Chen CT, Lee CJ, Shia KS, Shen MR.
Date:2022/03
Source:J Med Chem. 2022 Mar 24;65(6):4767-4782.
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