國立成功大學醫學院藥理學研究所

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Decreased plasma gelsolin fosters a fibrotic tumor microenvironment and promotes chemoradiotherapy resistance in esophageal squamous cell carcinoma

作者：Chih-Hsiung Hsieh, Pei-Shiuan Ho, Wen-Lun Wang, Fu-Hsuan Shih, Chen-Tai Hong, Pei-Wen Wang, Dar-Bin Shieh, Wei-Lun Chang & Yi-Ching Wang

出版年月：2024/09

出處：Journal of Biomedical Science

ADAR2 deficiency ameliorates non-alcoholic fatty liver disease and muscle atrophy through modulating serum amyloid A1

作者：Mei-Lang Kung, Tai-Hua Yang, Chia-Chi Lin, Jia-Yun Ho, Tzu-Chi Hung, Chih-Hsiang Chang, Kuan-Wen Huang, Chien-Chin Chen, Yun-Wen Chen*

出版年月：2024/06

出處：J Cachexia Sarcopenia Muscle . 2024 Jun;15(3):949-962.

Deficiency of ADAR2 ameliorates metabolic-associated fatty liver disease via AMPK signaling pathways in obese mice

作者：Mei-Lang Kung, Siao Muk Cheng, Yun-Han Wang, Kai-Pi Cheng, Yu-Lin Li, Yi-Tsen Hsiao, Bertrand Chin-Ming Tan & Yun-Wen Chen*

出版年月：2024/05

出處：Commun Biol . 2024 May 17;7(1):594

Rab37 mediates trafficking and membrane presentation of PD-1 to sustain T cell exhaustion in lung cancer.

作者：Kuo WT, Kuo IY, Hsieh HC, Wu ST, Su WC, Wang YC

出版年月：2024/02

出處：J Biomed Sci. 2024 Feb 7;31(1):20.doi: 10.1186/s12929-024-01009-6.PMID: 38321486

Downregulation of microRNA 326 enhances ZNF322A expression transcrip activity and tumorigenic effects in lung cancer

作者：Shih-Hsuan Huang,Hung-Chia Hsieh,Jiunn-Min Shieh,Wou-Chou Su,Yi-Ching Wang

出版年月：2023/08

出處：BioFactors. 2023;1–14.

UBE1C is upregulated and promotes neddylation of p53 in lung cancer

作者：Liu H, Shih YH, Wang WL, Chang WL, Wang YC.

出版年月：2023/10

出處：FASEB J. 2023 Oct;37(10):e23181. doi: 10.1096/fj.202300629R.

Dysregulation of SOX17/NRF2 axis confers chemoradiotherapy resistance and emerges as a novel therapeutic target in esophageal squamous cell carcinoma

作者：Chih-Hsiung Hsieh, Wen-Hui Kuan, Wei-Lun Chang, I-Ying Kuo, Hsun Liu, Dar-Bin Shieh, Hsuan Liu, Bertrand Tan & Yi-Ching Wang

出版年月：2022/10

出處：Journal of Biomedical Science volume 29, Article number: 90 (2022)

Development of a cancer cells self‑activating and miR‑125a‑5p expressing poly‑pharmacological nanodrug for cancer treatment.

作者：Chang YC, Shieh MC, Chang YH, Huang WL, Su WC, Cheng FY, Cheung CHA.

出版年月：2022/08

出處：Int J Mol Med. 2022 Aug;50(2):102.

The double-edged sword effect of HDAC6 in Aβ toxicities.

作者：Cheng KC, Hwang YL, Chiang HC.

出版年月：2022/01

出處：FASEB J. 2022 Jan;36(1):e22072. doi: 10.1096/fj.202101061R.

Early Aβ42 Exposure Causes Learning Impairment in Later Life

作者：Cheng KC, Cheung CHA, Chiang HC.

出版年月：2022/06

出處：Aging Dis. 2022 Jun 1;13(3):868-883. doi: 10.14336/AD.2021.1015. eCollection 2022 Jun.

Disrupted cellular calcium homeostasis is responsible for Aβ-induced learning and memory damage and lifespan shortening in a model of Aβ transgenic fly

作者：Cheng KC, Huang CY, Hsieh TC, Chiang HC.

出版年月：2022/08

出處：IUBMB Life. 2022 Aug;74(8):754-762. doi: 10.1002/iub.2621.

A dorsal CA2 to ventral CA1 circuit contributes to oxytocinergic modulation of long-term social recognition memory

作者：Tsai TC, Fang YS, Hung YC, Hung LC, Hsu KS.

出版年月：2022/07

出處：J Biomed Sci .

Distinct Contribution of Granular and Agranular Subdivisions of the Retrosplenial Cortex to Remote Contextual Fear Memory Retrieval

作者：Tsai TC, Yu TH, Hung YC, Fong LI, Hsu KS.

出版年月：2022/02

出處：J Neurosci. 2022 Feb 2;42(5):877-893.

TNFα-mediated necroptosis in brain endothelial cells as a potential mechanism of increased seizure susceptibility in mice following systemic inflammation

作者：Huang WY, Lai YL, Liu KH, Lin S, Chen HY, Liang CH, Wu HM, Hsu KS.

出版年月：2022/02

出處：J Neuroinflammation. 2022 Feb 2;19(1):29.

Discovery of Potential Neuroprotective Agents against Paclitaxel-Induced Peripheral Neuropathy.

作者：Chen YF, Wu CH, Chen LH, Lee HW, Lee JC, Yeh TK, Chang JY, Chou MC, Wu HL, Lai YP, Song JS, Yeh KC, Chen CT, Lee CJ, Shia KS, Shen MR.

出版年月：2022/03

出處：J Med Chem. 2022 Mar 24;65(6):4767-4782.

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