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Deubiquitinase USP24 activated by IL-6/STAT3 enhances PD-1 protein stability and suppresses T cell antitumor response

Deubiquitinase USP24 activated by IL-6/STAT3 enhances PD-1 protein stability and suppresses T cell antitumor response
作者：Hung-Chia Hsieh, Ming-Jer Young,Kuan-Yu Chen, Wu-Chou Su, Chien-Chung Lin, Yi-Ting Yen,Jan-Jong Hung and Yi-Ching Wang
出版年月：2025/04
出處：Science Advances 16 Apr 2025 Vol 11, Issue 16 DOI: 10.1126/sciadv.adt4258

Decreased plasma gelsolin fosters a fibrotic tumor microenvironment and promotes chemoradiotherapy resistance in esophageal squamous cell carcinoma

Decreased plasma gelsolin fosters a fibrotic tumor microenvironment and promotes chemoradiotherapy resistance in esophageal squamous cell carcinoma
作者：Chih-Hsiung Hsieh, Pei-Shiuan Ho, Wen-Lun Wang, Fu-Hsuan Shih, Chen-Tai Hong, Pei-Wen Wang, Dar-Bin Shieh, Wei-Lun Chang & Yi-Ching Wang
出版年月：2024/09
出處：Journal of Biomedical Science

ADAR2 deficiency ameliorates non-alcoholic fatty liver disease and muscle atrophy through modulating serum amyloid A1

ADAR2 deficiency ameliorates non-alcoholic fatty liver disease and muscle atrophy through modulating serum amyloid A1
作者：Mei-Lang Kung, Tai-Hua Yang, Chia-Chi Lin, Jia-Yun Ho, Tzu-Chi Hung, Chih-Hsiang Chang, Kuan-Wen Huang, Chien-Chin Chen, Yun-Wen Chen*
出版年月：2024/06
出處：J Cachexia Sarcopenia Muscle . 2024 Jun;15(3):949-962.

Deficiency of ADAR2 ameliorates metabolic-associated fatty liver disease via AMPK signaling pathways in obese mice

Deficiency of ADAR2 ameliorates metabolic-associated fatty liver disease via AMPK signaling pathways in obese mice
作者：Mei-Lang Kung, Siao Muk Cheng, Yun-Han Wang, Kai-Pi Cheng, Yu-Lin Li, Yi-Tsen Hsiao, Bertrand Chin-Ming Tan & Yun-Wen Chen*
出版年月：2024/05
出處：Commun Biol . 2024 May 17;7(1):594

Rab37 mediates trafficking and membrane presentation of PD-1 to sustain T cell exhaustion in lung cancer.

Rab37 mediates trafficking and membrane presentation of PD-1 to sustain T cell exhaustion in lung cancer.
作者：Kuo WT, Kuo IY, Hsieh HC, Wu ST, Su WC, Wang YC
出版年月：2024/02
出處：J Biomed Sci. 2024 Feb 7;31(1):20.doi: 10.1186/s12929-024-01009-6.PMID: 38321486

Downregulation of microRNA 326 enhances ZNF322A expression transcrip activity and tumorigenic effects in lung cancer

Downregulation of microRNA 326 enhances ZNF322A expression transcrip activity and tumorigenic effects in lung cancer
作者：Shih-Hsuan Huang,Hung-Chia Hsieh,Jiunn-Min Shieh,Wou-Chou Su,Yi-Ching Wang
出版年月：2023/08
出處：BioFactors. 2023;1–14.
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