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Latest Research

BDNF Val66Met protects oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer

Author:Li-Hsien Chen; Peng-Chan Lin; Yu-Min Yeh; Chung-I Li; Lian-Yun Chang; Jang-Yang Chang; Meng-Ru Shen*
Date:2026/02
Source:Science Translational Medicine 18 Feb 2026 , Vol 18, Issue 837

Decreased plasma gelsolin fosters a fibrotic tumor microenvironment and promotes chemoradiotherapy resistance in esophageal squamous cell carcinoma

Author:Chih-Hsiung Hsieh, Pei-Shiuan Ho, Wen-Lun Wang, Fu-Hsuan Shih, Chen-Tai Hong, Pei-Wen Wang, Dar-Bin Shieh, Wei-Lun Chang & Yi-Ching Wang
Date:2024/09
Source:Journal of Biomedical Science (2024) 31:90

Dysregulation of SOX17/NRF2 axis confers chemoradiotherapy resistance and emerges as a novel therapeutic target in esophageal squamous cell carcinoma

Author:Chih-Hsiung Hsieh, Wen-Hui Kuan, Wei-Lun Chang, I-Ying Kuo, Hsun Liu, Dar-Bin Shieh, Hsuan Liu, Bertrand Tan & Yi-Ching Wang
Date:2022/10
Source:Journal of Biomedical Science volume 29, Article number: 90 (2022)

The double-edged sword effect of HDAC6 in Aβ toxicities.

Author:Cheng KC, Hwang YL, Chiang HC.
Date:2022/01
Source:FASEB J. 2022 Jan;36(1):e22072. doi: 10.1096/fj.202101061R.

Early Aβ42 Exposure Causes Learning Impairment in Later Life.

Author:Cheng KC, Cheung CHA, Chiang HC.
Date:2022/06
Source:Aging Dis. 2022 Jun 1;13(3):868-883

Disrupted cellular calcium homeostasis is responsible for Aβ-induced learning and memory damage and lifespan shortening in a model of Aβ transgenic fly.

Author:Cheng KC, Huang CY, Hsieh TC, Chiang HC.
Date:2022/08
Source:IUBMB Life. 2022 Aug;74(8):754-762.

Development of a cancer cells self‑activating and miR‑125a‑5p expressing poly‑pharmacological nanodrug for cancer treatment

Author:Chang YC, Shieh MC, Chang YH, Huang WL, Su WC, Cheng FY, Cheung CHA.
Date:2022/08
Source:Int J Mol Med. 2022 Aug;50(2):102.

A dorsal CA2 to ventral CA1 circuit contributes to oxytocinergic modulation of long-term social recognition memory

Author:Tsai TC, Fang YS, Hung YC, Hung LC, Hsu KS.
Date:2022/07
Source:J Biomed Sci. 2022 Jul 10;29(1):50

Distinct Contribution of Granular and Agranular Subdivisions of the Retrosplenial Cortex to Remote Contextual Fear Memory Retrieval

Author:Tsai TC, Yu TH, Hung YC, Fong LI, Hsu KS.
Date:2022/02
Source:J Neurosci . 2022 Feb 2;42(5):877-893

TNFα-mediated necroptosis in brain endothelial cells as a potential mechanism of increased seizure susceptibility in mice following systemic inflammation

Author:Huang WY, Lai YL, Liu KH, Lin S, Chen HY, Liang CH, Wu HM, Hsu KS.
Date:2022/02
Source:J Neuroinflammation. 2022; 19: 29.
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