國立成功大學醫學院藥理學研究所

最新發表

An innovative NRF2 nano-modulator induces lung cancer ferroptosis and elicits an immunostimulatory tumor microenvironment

作者：Chih-Hsiung Hsieh, Hung-Chia Hsieh(謝宏嘉), Fu-Shiuan Shih, Pei-Wen Wang, Li-Xing Yang, Dar-Bin Shieh, Yi-Ching Wang

出版年月：2021/05

出處：Theranostics 2021; 11(14):7072-7091. doi:10.7150/thno.57803

Converged Rab37/IL-6 trafficking and STAT3/PD-1 transcrip axes elicit an immunosuppressive lung tumor microenvironment

作者：I-Ying Kuo, You-En Yan, Pei-Shan Yang, Yu-Jou Tsai, Hong-Tai Tzeng, Hung-Chi Cheng, Wan-Ting Kuo, Wu-Chou Su, Chih-Peng Chang, Yi-Ching Wang(王憶卿)

出版年月：2021/05

出處：Theranostics 2021; 11(14):7029-7044. doi:10.7150/thno.60040

Dysregulated Kras/YY1/ZNF322A/Shh axis trans-criptional enhances neo-angiogenesis to promote lung cancer progression

作者：Che-Chung Lin, I-Ying Kuo, Li-Ting Wu, Wen-Hui Kuan, Sheng-You Liao, Jayu Jen, You-En Yang, Cheng-Wei Tang, Yi-Rong Chen, Yi-Ching Wang

出版年月：2020/08

出處：Theranostics 2020; 10(22):10001-10015. doi:10.7150/thno.47491

Oleic acid-induced NOX4 is dependent on ANGPTL4 expression to promote human colorectal cancer metastasis

作者：Shen CJ, Chang KY, Lin BW, Lin WT, Su CM, Tsai JP, Liao YH, Hung LY, Chang WC, Chen BK.

出版年月：2020/05

出處：Theranostics.10(16):7083-7099.

Author Correction: Germline susceptibility variants impact clinical outcome and therapeutic strategies for stage III colorectal cancer

作者：Lin PC, Yeh YM, Wu PY, Hsu KF, Chang JY, Shen MR.

出版年月：2020/07

出處：Sci Rep. 2020 Jul 17;10(1):12216. doi: 10.1038/s41598-020-69145-1.

Exposure to Novelty Promotes Long-Term Contextual Fear Memory Formation in Juvenile Mice: Evidence for a Behavioral Tagging

作者：Chen N, Tsai TC, Hsu KS.

出版年月：2020/09

出處：Mol Neurobiol. 2020 Sep;57(9):3956-3968. doi: 10.1007/s12035-020-02005-1.

Inhibition of Sonic Hedgehog Signaling Suppresses Glioma Stem-Like Cells Likely Through Inducing Autophagic Cell Death

作者：Hung HC, Liu CC, Chuang JY, Su CL, Gean PW.

出版年月：2020/07

出處：Front Oncol. 2020 Jul 24;10:1233. doi: 10.3389/fonc.2020.01233. eCollection 2020.

The SMAC mimetic LCL161 is a direct ABCB1/MDR1-ATPase activity modulator and BIRC5/Survivin expression down-regulator in cancer cells.

作者：Chang YC, Kondapuram SK, Yang TH, Syed SB, Cheng SM, Lin TY, Lin YC, Coumar MS, Chang JY, Leung E, Cheung CHA.

出版年月：2020/08

出處：Toxicol Appl Pharmacol.

BIRC5/Survivin is a novel ATG12-ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells

作者：Lin TY, Chan HH, Chen SH, Sarvagalla S, Chen PS, Coumar MS, Cheng SM, Chang YC, Lin CH, Leung E, Cheung CHA.

出版年月：2020/07

出處：Autophagy.

MicroRNA-206 Regulates Stress-Provoked Aggressive Behaviors in Post-weaning Social Isolation Mice

作者：Chang CH, Kuek EJW, Su CL, Gean PW.

出版年月：2020/06

出處：Mol Ther Nucleic Acids.

ST2 Signaling in the Tumor Microenvironment

作者：Chang CP, Hu MH, Hsiao YP, Wang YC.

出版年月：2020/02

出處：Adv Exp Med Biol.

Epidermal Growth Factor-Induced COX-2 Regulates Metastasis of Head and Neck Squamous Cell Carcinoma Through Upregulation of Angiopoietin-Like 4

作者：Kuo-Hwa Chiang , Jiunn-Min Shieh , Chih-Jie Shen, Ting-Wei Chang , Pei-Ting Wu , Jinn-Yuan Hsu , Jhih-Peng Tsai , Wen-Chang Chang , Ben-Kuen Chen

出版年月：2020/03

出處：Cancer Sci.

Targeting interleukin-20 Alleviates Paclitaxel-Induced Peripheral Neuropathy

作者：Chen LH, Yeh YM, Chen YF, Hsu YH, Wang HH, Lin PC, Chang LY, Lin CK, Chang MS, Shen MR.

出版年月：2020/01

出處：pain.

NADPH Oxidase 2 as a Potential Therapeutic Target for Protection Against Cognitive Deficits Following Systemic Inflammation in Mice

作者：Huang WY, Liu KH, Lin S, Chen TY, Tseng CY, Chen HY, Wu HM, Hsu KS.

出版年月：2020/02

出處：Brain Behav Immun.

Transcranial Direct Current Stimulation Alleviates Seizure Severity in Kainic Acid-Induced Status Epilepticus Rats

作者：Wu YJ, Chien ME, Huang CH, Chiang CC, Lin CC, Huang CW, Durand DM, Hsu KS.

出版年月：2020/06

出處：Exp Neurol.

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